Phosphopantetheine-binding protein

Author: rbcy

August undefined, 2024

WebAug 31, 2015 · In vitro experiments have shown that in addition to vitamin B5, pantetheine can also be phosphorylated by pantothenate kinase activity, and the formed product, 4′-phosphopantetheine, can serve as... WebThe OUROBOROS and SAMSARA proteins heterodimerise in a similar manner to TALE HD TF life cycle regulators in the green lineage. These observations demonstrate that TALE-HD-TF-based life cycle regulation systems have an extremely ancient origin, and that these systems have been independently recruited to regulate sporophyte developmental ...

Phosphopantetheine-binding protein (Salinispora tropica)

WebOct 5, 2001 · 4'-Phosphopantetheine transferases (PPTases) transfer the 4'-phosphopantetheine moiety of coenzyme A onto a conserved serine residue of acyl … WebMar 8, 2024 · A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and … how much power does a sam turret need

C7QAF4 - UniProt

WebAlthough holo-acyl carrier protein synthase, AcpS, a phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until the publication of the landmark paper by Lambalot et al.in 1996 that PPTases garnered wide-spread attention being classified as a distinct enzyme superfamily. WebPhosphopantetheine-binding protein (Pectobacterium carotovorum PC1) - STRING interaction network Nodes: Network nodes represent proteins splice isoforms or post … Webprotein Summary Phosphopantetheine-binding protein (Streptomyces rimosus subsp. rimosus ATCC 10970) Cite Download Contents 1 Sequence 2 Interactions and Pathways 3 … how do market economies produce

Bpro_0765 - Phosphopantetheine-binding protein

CDD Conserved Protein Domain Family: PP-binding - National …

WebProtein Phosphopantetheine-binding Status UniProtKB unreviewed (TrEMBL) Organism Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908) Amino acids 92 Protein existence Predicted Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add Add a publication Entry … WebJan 3, 2024 · Using E. coli LipB as a prototype, we show that the enzyme mainly recognizes the 4’-phosphopantetheine tethered acyl-chain of its donor substrate, and weakly binds the apo-acyl carrier protein. It can accept octanoate-from its own ACP, noncognate ACPs, as well as C 8 -CoA. how much power does a shower useWebPlease help us improve further — take a moment to fill our brief user survey. how do market forces affect organisations

"WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl … " - Phosphopantetheine-binding protein

Phosphopantetheine-binding protein

A novel adenylate binding site confers phosphopantetheine ...

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. …

Did you know?

WebJun 3, 2010 · Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine. ... Find proteins for P9WPA5 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WPA5 . Go to UniProtKB: P9WPA5. Entity Groups Sequence Clusters: WebThe mitochondrial acyl carrier protein (human ACPM, yeast Acp1) is an essential mitochondrial protein. Through binding of nascent acyl chains on the serine (S112)-bound 4′-phosphopantetheine (4′-PP) cofactor, ACPM is involved in mitochondrial fatty acid synthesis and lipoic acid biogenesis. Recently, yeast A Molecular Pharmacology

WebPhosphopantetheine adenylyltransferase (PPAT, EC. 2.7.7.3) catalyzes an essential step in the reaction that transfers an adenylyl group from adenosine tri phosphate (ATP) to 4' … Webphosphopantetheine-binding protein: copy AA seq copy Nt seq. PpisJ2_010100002376; WP_010369400.1; 206556 - 208052 (+) AMP-binding protein: copy AA seq copy Nt seq. PpisJ2_010100002381; WP_010369404.1; 208045 - 210228 (+) beta-ketoacyl-[acyl-carrier-protein] synthase family protein: copy AA seq

WebBinding to a protein. ... 4'-Phosphopantetheinyl transferases (PPTs) catalyze the transfer of 4'-phosphopantetheine (4-PP) from coenzyme A to a conserved serine residue of their protein substrates. In humans, the number of pathways utilizing the 4-PP post-translational modification is limited and may only require a single broad specificity PPT ... WebThe acyl carrier protein ( ACP) is a cofactor of both fatty acid and polyketide biosynthesis machinery. It is one of the most abundant proteins in cells of E. coli. [1] In both cases, the …

WebProteomics of Streptococcus mutans to Reveal the Antibiofilm Formation Mechanism of Ag/ZnO Nanocomposites with Light-Emitting Diode Radiation

WebJan 8, 2024 · 4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function 4'-Phosphopantetheine and long acyl … how do marker fossils relate to geologic timeWebJan 18, 1999 · Each phosphopantetheine adenylyltransferase (PPAT) subunit displays a dinucleotide-binding fold that is structurally similar to that in class I aminoacyl-tRNA synthetases. Superposition of bound adenylyl moieties from dPCoA in PPAT and ATP in aminoacyl-tRNA synthetases suggests nucleophilic attack by the 4'-phosphopantetheine … how much power does a neon light useWebphosphopantetheine-binding protein 61012291 - Gene ResultWI98_RS26710 phosphopantetheine-binding protein [] Gene provides a unified query environment for … how much power does a slow cooker useWebApr 26, 2024 · This protein belongs to the phosphopantetheine attachment site (IPR006162) and other protein classes of databases InterPro, pfam, and TIGRfam like srf AA. The genome also possesses gene srf AD (729 bp) encodes for the thioesterase domain-containing protein comprising 242 amino acids. how do market forces affect the nhsWebJul 21, 2024 · The phosphopantetheine-binding domain (PP-binding superfamily), conserved in ACP proteins, is the prosthetic group of ACP, which acts as a linker for the attachment of the activated FA and amino acid groups via a phosphodiester bond ( Crawford et al. 2008; Meier et al. 2010; Roujeinikova et al. 2002 ). how much power does a thermostat useWebFeb 1, 2024 · The reaction mechanism of PPAT involves a nucleophilic attack by 4′-phosphate of phosphopantetheine on the α-phosphate of ATP in an in-line displacement mechanism, where both the substrates are positioned in a single line. This results in a short lived intermediate pentacovalent transition state. how much power does a solar panel generateWebMar 3, 2006 · In most bacteria, the so-called Dfp proteins catalyze the synthesis of the coenzyme A precursor 4′-phosphopantetheine. Dfp proteins are bifunctional enzymes catalyzing the synthesis of 4′-phosphopantothenoylcysteine (CoaB activity) and its decarboxylation to 4′-phosphopantetheine (CoaC activity). ... (maltose-binding protein) … how much power does a small refrigerator use