WebApr 11, 2024 · This is a phase II randomized, observer-blinded, placebo-controlled study with 3 arms enrolling a total of 2,358 participants. The arms are composed of Arm 1, pregnant participants receiving Hecolin® (N=1,104) with immunogenicity subset (n=150), Arm 2, pregnant participants receiving placebo (N=1,104) with immunogenicity subset (n=150), … WebApr 10, 2024 · Neutralizing antibody titers were determined by a plaque reduction assay. Therefore, serial serum or monoclonal antibodies dilutions were incubated with 100 plaque-forming units (pfu) of the SARS-CoV-2 isolates for 1 h. The mixture was dispersed on VeroE6 cells in a 12-well format and cells were overlaid with 0.6% oxoid-agar for 72 h at 37 °C.
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