WebBoth tobacco and Arabidopsis thaliana GrpE homologues bound to DnaK and ATP inhibited this binding. The tobacco GrpE homologue contained a typical N-terminal mitochondrial target presequence of 64 residues and the presequence directed the green fluorescent protein to tobacco mitochondria. WebMar 8, 2024 · In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as ...
Q0UL32 - UniProt
WebAbstract. The cochaperone GrpE functions as a nucleotide exchange factor to promote dissociation of adenosine 5'-diphosphate (ADP) from the nucleotide-binding cleft of … WebSummary Gene: Grpel1 (GrpE-like 1, mitochondrial) Rattus norvegicus Add Watcher Analyze General Array IDs Annotation Click to see Annotation Detail View Disease … rehashop schwellenrampe
GRPEL1 - GrpE protein homolog 1, mitochondrial
WebApr 11, 2024 · In multiple cancers, slow-dividing cancer cells generate ATP via mitochondrial oxidative phosphorylation . Besides, cancer stem cells, which are resistant to regular chemo- and radiotherapy, ... Aaron Ciechanover used yeast mutants to clone human homolog genes involved in protein ubiquitination, previously studied in the budding … WebGrpE protein homolog 1, mitochondrial Alternative names Mt-GrpE#1 Gene names Name Grpel1 Synonyms Grepel1 Organism names Organism Rattus norvegicus (Rat) Taxonomic identifier 10116 NCBI Taxonomic lineage WebAug 17, 2024 · We also show that matrix-localized GrpE protein homolog 1 (GrpEL1), a cochaperone of mitochondrial Hsp70 (mtHsp70), is also the substrate of dengue virus protease, as observed in vitroand ex vivoin virus-infected cells and dengue virus-infected … rehashop seniorenbett